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双香豆素,≥98%

Q0203G
Dicoumarol
3,3'-亚甲基二(4-羟基-2H-苯并吡喃-2-酮) 3,3'-亚甲基二(4-羟基-2H-苯并吡喃-2-酮) 展开
66-76-2
RT避光
1年
货号 规格 目录价 优惠价 会员价 库存(北京) 哈尔滨 沈阳 广州 数量 购物车
Q0203G 1g ¥238.00
中文名称 双香豆素
中文别名 3,3'-亚甲基二(4-羟基-2H-苯并吡喃-2-酮)
英文名称 Dicoumarol
英文别名 3,3'-Methylenebis(4-hydroxy-2H-chromen-2-one)
CAS号 66-76-2
分子式 C19H12O6
分子量 336.29
溶解性 溶于吡啶(50mg/ml)
纯度: ≥98%
产品介绍:

一种NAD(P)H:醌氧化还原酶1(NQO1)和PDK1的抑制剂。

Dicoumarol (INN) or dicumarol (USAN) is a naturally occurring anticoagulant that functions as a functional vitamin K depleter (similar to warfarin, a drug that dicoumarol inspired). It is also used in biochemical experiments as an inhibitor of reductases. Like all 4-hydroxycoumarin drugs it is a competitive inhibitor of vitamin K epoxide reductase, an enzyme that recycles vitamin K, thus causing depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes. These compounds are not antagonists of Vitamin K directly—as they are in pharmaceutical uses—but rather promote depletion of vitamin K in bodily tissues allowing vitamin K's mechanism of action as a potent medication for dicoumarol toxicity. The mechanism of action of Vitamin K along with the toxicity of dicoumarol are measured with the prothrombin time (PT) blood test.

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注意:

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。 

 

备注:
以上数据均来自公开文献,博奥拓达暂未进行独立验证,仅供参考。
These protocols are for reference only. Biotopped does not independently validate these methods.

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暂无 质检报告(COA)!
暂无技术问答内容!

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